Because of FEP’s inherent inertness and because Holscot had the techniques to extrude and weld FEP, it was chosen as being the ideal material. The bag was formed from an extrusion in FEP which was folded over and welded at the end but, at the inlet end, a special sealing arrangement onto the end plate had to be developed. The resultant bags were subjected to irradiation to ensure the sterility of the bags in use.